NFL Week 5 Betting Odds & Analysis | PA Online Sportsbooks

Week five of NFL action brings us plenty of juicy matchups to pick from. The Chargers will host the Broncos in what looks like quite the mismatch. The Bills travel to Tennessee to take on the unpredictable Titans. Let’s take a look at the likely outcomes of this week’s NFL games.

Arizona Cardinals +3 at Cincinnati Bengals -3 O/U 46.5

Kyler Murray has flashed some signs of greatness yet the Cardinals defense has let him down across the first quarter of the season. Arizona should win this week’s matchup against the lowly Bengals. Cincinnati placed wide receiver John Ross on injured reserve due to his shoulder injury. The team’s other star wide receiver, A.J. Green, probably won’t play due to his lingering foot injury. Arizona is due for a win and it will likely come against a banged up Cincy squad on the road.

Pick: Arizona moneyline +152

Buffalo Bills +3 at Tennessee Titans -3 O/U 38.5

The Bills and Titans are difficult to handicap as they both have schizophrenic offenses. Josh Allen might not play as he is dealing with concussion symptoms. However, backup quarterback Matt Barkley is a solid game manager. The Bills might also be without running back Devin Singletary. If Allen is out, this will likely be a low-scoring game in which Tennessee plays ball control offense against the Bills elite pass defense.

Pick: Under 38.5

Chicago Bears -5 at Oakland Raiders +5 O/U 40.5

Oakland’s offense looked spectacular last week against the Colts. Things will be much different this week as the Raiders take on the Bears elite defenders. Though Chicago quarterback Mitch Trubisky might not suit up for this matchup due to a shoulder injury, Chase Daniel is a serviceable backup. SugarHouse’s line of Oakland +5 is too tempting to pass up.

Pick: Raiders +5

Minnesota Vikings -5.5 at New York Giants +5.5 O/U 43.5

The Vikings struggled to score last week even though the team’s offense is nearly 100% healthy. The Giants have been red-hot since Daniel Jones took over at QB for Eli Manning. The G-Men might also get Saquon Barkley back this week. However, there is the potential for the Vikings talented offense to figure things out and put up 20-30 points against an underwhelming Giants defense. This just might be the week the Vikings open things up with their passing game.

Pick: Over 43.5

Jacksonville Jaguars +3.5 at Carolina Panthers -3.5 O/U 41

This matchup will feature two quarterbacks who were relatively unknown prior to the start of the season: Gardner Minshew and Kyle Allen. Both quarterbacks have been surprisingly effective in limited action. However, the Jaguars have the superior defense and it looks like their top cornerback Jalen Ramsey will not be traded before this game kicks off.

Pick: Jaguars +3.5

Denver Broncos +6.5 at Los Angeles Chargers -6.5 O/U 44.5

The Chargers are listed as nearly a full touchdown favorite against the Broncos as Melvin Gordon will return as the starting running back following the end of his holdout. The Broncos have been as disappointing as it gets. Look for the Chargers to win this one with ease.

Pick: Chargers moneyline -270

Green Bay Packers +3.5 at Dallas Cowboys -3.5 O/U 46.5

The Cowboys covered the 2 point spread last week against the Teddy Bridgewater-led Saints. However, Dallas should have easily won that game as Bridgewater is a second tier NFL QB. It looks like Michael Gallup will be out for this game due to injury.  SugarHouse has the Cowboys as 3.5 point favorites as this is a home game. Look for Dallas to prevail in a tight contest in big D.

Pick: Cowboys moneyline -190

Indianapolis Colts +11 at Kansas City Chiefs -11 O/U 56

The Colts were incredibly disappointing last week against the Raiders. As a result, SugarHouse has Indy listed as an 11 point dog to the Chiefs. Kansas City should roll to an easy victory in this home matchup unless the Colts can control the clock with Marlon Mack rushes. It is much more likely Indy will be in a big hole by the end of the first quarter and have to rely on the pass to score points. If T.Y. Hilton appears near 100% for this matchup, take the over.

Pick: Over 56

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